Along with glucosamine, MSM, and perna canaliculus, Glyco-Flex III contains other ingredients such as N.N. Dimethyliglycine (DMG), Vitamins C and E, Selenium, Manganese, grape seed extract, and L-Glutathione. Vetriscience holds 5 US patents on DMG which demonstrates the multiple benefits that this ingredient can provide for the health and well-being of the dog.